Om / Discovery / Open Pipeline Challenges
My submissions →Om Open Pipeline Challenges
Predict the binder.We’ll test it.
Each challenge names one protein. Use Om's agentic small-molecule discovery models and capabilities—or your own methods—to find binders. Submit your predictions and Om will procure and experimentally test every accepted molecule by AS-MS. You own the Result Data.
How it works
One molecule. One owned result.
One protein at a time
Discover
01
Om 50
Use LULA, Om’s agentic tools, or your own methods
Submit
02
5,000
Wallet Credits for each molecule Om accepts
Validate
03
AS-MS
Om tests every accepted molecule against the challenge protein
Get paid
04
Posted rate
for each payout-selected Qualified Binder licensed for model improvement
Your data
You own every result.
You decide whether your molecule and final result are made public.
Qualified Binder payouts
$25K
Featured maximum payout
Every protein publishes its payment per Qualified Binder and the number of payments available. Earlier paid submissions are considered first. Paid Qualified Binder data helps improve models Om makes available to researchers globally.
Protein targets
Open Pipeline Challenges
Loading challenges
Reading the current protein challenges.
Choose molecules
Use LULA, Om's agentic API and MCP capabilities, or your own methods to select molecules from the challenge's pinned om_50 catalog.
Paste SMILES
Paste one SMILES per line. Each accepted molecule costs 5,000 Wallet Credits, with no participant submission limit.
Validate by AS-MS
Om prepares the protein and tests every accepted molecule by AS-MS. You own each result. For a payout-selected Qualified Binder, Om pays the posted amount for a non-exclusive license to use that result for model improvement.